Symbol
Name
ID

Itgb3
integrin beta 3
MGI:96612

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes	Gastrointestinal hemorrhage	Intracranial hemorrhage	Subdural hemorrhage	Joint hemorrhage	Bruising susceptibility	Purpura	Ecchymosis	Petechiae	Spontaneous hematomas
Disease(s) Associated with ITGB3	Gastrointestinal hemorrhage	Intracranial hemorrhage	Subdural hemorrhage	Joint hemorrhage	Bruising susceptibility	Purpura	Ecchymosis	Petechiae	Spontaneous hematomas
Glanzmann's thrombasthenia
platelet-type bleeding disorder 16
thrombocytopenia

Mouse Phenotypes

abnormal induced retina neovascularization

abnormal physiological neovascularization

abnormal tumor vascularization

increased angiogenesis

heart left ventricle hypertrophy

increased heart weight

cardiac hypertrophy

increased heart left ventricle weight

hemorrhage

uterine hemorrhage

gastrointestinal hemorrhage

intracranial hemorrhage

skin hemorrhage

decreased cardiac muscle contractility

abnormal cardiac muscle relaxation

decreased left ventricle systolic pressure

increased left ventricle diastolic pressure

decreased heart rate

increased response of heart to induced stress

Availability

Mouse Genotype

Itgb3^tm1Hyn/Itgb3^tm1Hyn

Itgb3^tm1Mgin/Itgb3^tm1Mgin

Itgb3^tm2Mgin/Itgb3^tm2Mgin

Itgb3^tm1Hyn/Itgb3⁺

Itgb3^tm1Hyn/Itgb3^tm1.1Wlbcr
Tg(Pf4-icre)Q3Rsko/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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